Prognostic value of p16 expression in Epstein-Barr virus-positive nasopharyngeal carcinomas.

Wen JiangPaul D ChamberlainAdam S GardenBetty Y S KimDominic MaEmily J LoDiana BellG Brandon GunnClifton D FullerDavid I RosenthalBeth M BeadleSteven J FrankWilliam H MorrisonAdel K El-NaggarBonnie S GlissonErich M SturgisJack Phan

Published in: Head & neck (2015)

P16 overexpression is associated with improved PFS and locoregional control in patients with EBV-positive NPC. P16 expression may complement EBV status in predicting treatment outcomes for patients with NPC. © 2015 Wiley Periodicals, Inc. Head Neck 38: E1459-E1466, 2016.

Keyphrases

epstein barr virus
diffuse large b cell lymphoma
poor prognosis
binding protein
cell proliferation
transcription factor
high grade
optic nerve