Cerebral microbleeds in a neonatal rat model.

Brianna C TheriaultSeung Kyoon WooJason K KarimyKaspar KeledjianJesse A StokumAmrita SarkarTurhan CoksayganSvetlana IvanovaVolodymyr GerzanichJ Marc Simard

Published in: PloS one (2017)

In rats, pro-angiogenic stimuli in utero can predispose to vascular fragility and lead to cerebral microbleeds. The study of microbleeds in the neonatal rat brain at full gestation may give insights into the consequences of microbleeds in human preterm infants during critical periods of white matter development.

Keyphrases

preterm infants
white matter
subarachnoid hemorrhage
low birth weight
endothelial cells
cerebral ischemia
multiple sclerosis
induced pluripotent stem cells
gestational age
pluripotent stem cells
preterm birth