High expression of Toll-like receptor 7 is a survival factor in pediatric medulloblastoma.

Lourdes Alvarez-ArellanoPilar Eguía-AguilarPatricia Piña-SánchezNadia González-GarcíaAlam Palma-GuzmanMario Perezpeña-DiazcontiCarmen Maldonado-Bernal

Published in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2021)

Medulloblastomas present cellular infiltration and a differential expression of TLRs depending on the histological subtype. TLR7 is a prognostic factor of survival that is dependent on treatment and age.

Keyphrases

toll like receptor
prognostic factors
nuclear factor
inflammatory response
immune response
poor prognosis
free survival
binding protein
young adults
smoking cessation