Restoration of miR-340 controls pancreatic cancer cell CD47 expression to promote macrophage phagocytosis and enhance antitumor immunity.

Qing XiJieyou ZhangGuangze YangLijuan ZhangYing ChenChengzhi WangZimu ZhangXiangdong GuoJingyi ZhaoZhenyi XueYan LiQi ZhangYurong DaLi LiuZhi YaoRongxin Zhang

Published in: Journal for immunotherapy of cancer (2021)

miR-340 is a key regulator of phagocytosis and antitumor immunity, and it could offer a new opportunity for immunotherapy for PDAC.

Keyphrases

long non coding rna
cell proliferation
poor prognosis
long noncoding rna
single cell
cell therapy
adipose tissue
transcription factor
stem cells
binding protein