Neuronal nitric oxide synthase regulates regional brain perfusion in healthy humans.
Kevin O'GallagherFrancesca PuleddaOwen O'DalyMatthew RyanLuke DancyPhilip J ChowienczykFernando ZelayaPeter J GoadsbyAjay M ShahPublished in: Cardiovascular research (2021)
These data suggest a fundamental physiological role of nNOS in regulating regional CBF and functional connectivity in the human hippocampus. Our findings have relevance to the role of nNOS in the regulation of cerebral perfusion in health and disease.
Keyphrases
- nitric oxide synthase
- functional connectivity
- resting state
- cerebral ischemia
- nitric oxide
- subarachnoid hemorrhage
- endothelial cells
- contrast enhanced
- healthcare
- public health
- mental health
- blood brain barrier
- electronic health record
- induced pluripotent stem cells
- brain injury
- pluripotent stem cells
- health information
- big data
- magnetic resonance imaging
- multiple sclerosis
- magnetic resonance
- risk assessment
- human health