Recent Development of Rhenium-Based Materials in the Application of Diagnosis and Tumor Therapy.
Qingwen QiQian WangYu-Hao LiDionisio Zaldivar SilvaMaria Eliana Lanio RuizRuizhuo OuyangBaolin LiuYuqing MiaoPublished in: Molecules (Basel, Switzerland) (2023)
Rhenium (Re) is widely used in the diagnosis and treatment of cancer due to its unique physical and chemical properties. Re has more valence electrons in its outer shell, allowing it to exist in a variety of oxidation states and to form different geometric configurations with many different ligands. The luminescence properties, lipophilicity, and cytotoxicity of complexes can be adjusted by changing the ligand of Re. This article mainly reviews the development of radionuclide 188 Re in radiotherapy and some innovative applications of Re as well as the different therapeutic approaches and imaging techniques used in cancer therapy. In addition, the current application and future challenges and opportunities of Re are also discussed.
Keyphrases
- cancer therapy
- early stage
- mental health
- papillary thyroid
- high resolution
- radiation therapy
- quantum dots
- squamous cell carcinoma
- radiation induced
- randomized controlled trial
- systematic review
- photodynamic therapy
- squamous cell
- locally advanced
- hydrogen peroxide
- young adults
- fluorescence imaging
- lymph node metastasis
- replacement therapy
- meta analyses