Using polyphenols as a relevant therapy to diabetes and its complications, a review.
José João Caires SerinaPaula Cristina Machado Ferreira CastilhoPublished in: Critical reviews in food science and nutrition (2021)
Diabetes is currently a worldwide health concern. Hyperglycemia, hypertension, obesity, and oxidative stress are the major risk factors that inevitably lead to all the complications from diabetes. These complications severely impact the quality of life of patients, and they can be managed, reduced, or even reverted by several polyphenols, plant extracts and foods rich in these compounds. The goal of this review is to approach diabetes not as a single condition but rather an interconnected combination of risk factors and complications. This work shows that polyphenols have multi target action and effects and they have been systematically proven to be relevant in the reduction of each risk factor and improvement of associated complication.
Keyphrases
- risk factors
- type diabetes
- cardiovascular disease
- glycemic control
- oxidative stress
- healthcare
- blood pressure
- end stage renal disease
- ejection fraction
- metabolic syndrome
- weight loss
- mental health
- stem cells
- dna damage
- physical activity
- skeletal muscle
- body mass index
- peritoneal dialysis
- ischemia reperfusion injury
- mesenchymal stem cells
- climate change
- signaling pathway
- patient reported outcomes
- health information
- health promotion
- smoking cessation