Maternal body mass index, early-pregnancy metabolite profile and birthweight.
Rama J WahabVincent W V JaddoeEllis VoermanGeorge J G RuijterJanine F FelixLinda MarchioroOlaf UhlEngy ShokryBerthold KoletzkoRomy GaillardPublished in: The Journal of clinical endocrinology and metabolism (2021)
A higher maternal prepregnancy BMI was associated with altered maternal early-pregnancy amino acids, non-esterified fatty acids, phospholipids and carnitines. Using these metabolites, we identified a maternal metabolite profile which improved prediction of birthweight in women with a higher prepregnancy BMI compared to glucose and lipid concentrations.