Increased Expression of Pyroptosis in Leukocytes of Patients with Kawasaki Disease.

Kuang-Che Kou Ya-Ling YangMao-Hung LoXin-Yuan CaiMindy Ming-Huey GuoHo-Chang Kuo Ying-Hsien Huang

Published in: Diagnostics (Basel, Switzerland) (2021)

Our study is the first to report the upregulation of pyroptotic caspase-1, -4, and -5 in peripheral leukocytes of KD patients. Moreover, the expression of caspase-3 may be associated with IVIG resistance in KD.

Keyphrases

poor prognosis
end stage renal disease
cell death
ejection fraction
newly diagnosed
peripheral blood
chronic kidney disease
long non coding rna
prognostic factors
binding protein
peritoneal dialysis
signaling pathway
nlrp inflammasome