Discovery of a proliferation essential gene signature and actin-like 6A as potential biomarkers for predicting prognosis and neoadjuvant chemotherapy response in triple-positive breast cancer.
Xiaofen LiShiping LuoWenfen FuMingyao HuangXiewei HuangShaohong KangJie ZhangQingshui WangChuan-Gui SongPublished in: Cancer (2024)
This efficient PEG signature prognostic model can predict the outcomes of TPBC. Furthermore, ACTL6A expression level was associated with the response to NACT, and could serve as an important factor in predicting prognosis and drug sensitivity of patients with TPBC.
Keyphrases
- neoadjuvant chemotherapy
- positive breast cancer
- locally advanced
- lymph node
- sentinel lymph node
- poor prognosis
- small molecule
- signaling pathway
- genome wide
- high throughput
- copy number
- squamous cell carcinoma
- rectal cancer
- emergency department
- binding protein
- radiation therapy
- cell migration
- long non coding rna
- single cell
- weight loss