Early changes of the heat-shock protein 60 to 70 ratio as prediction of miscarriage in pregnancy.

Aggeliki MakriCharalampos SiristatidisCharalampos ChreliasChrysi ChristodoulakiNikolaos EvangelinakisDimitrios KassanosEvangelos J Giamarellos-BourboulisAikaterini Pistiki

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2019)

A HSP60/HSP70 ratio equal to or more than 6 until gestational week 12 is accompanied with great likelihood for miscarriage. A similar ratio applies in an animal model of PTD induced by low-dose LPS.

Keyphrases

heat shock protein
low dose
heat shock
pregnant women
weight gain
inflammatory response
high dose
pregnancy outcomes
preterm birth
heat stress
randomized controlled trial
clinical trial
anti inflammatory
birth weight
study protocol