Genomic sequencing surveillance of patients colonized with vancomycin-resistant Enterococcus (VRE) improves detection of hospital-associated transmission.
Alexander J SundermannVatsala Rangachar SrinivasaEmma G MillsMarissa P GriffithEric EvansJieshi ChenKady D WaggleGraham M SnyderLora Lee PlessLee H HarrisonDaria Van TynePublished in: medRxiv : the preprint server for health sciences (2024)
Our findings describe the high burden of VRE transmission at our hospital and shed light on the importance of using WGS surveillance of both clinical and rectal screening isolates to better understand the transmission of this pathogen. This study highlights the potential utility of incorporating WGS surveillance of VRE into routine hospital practice for improving infection prevention and patient safety.
Keyphrases
- patient safety
- healthcare
- public health
- end stage renal disease
- quality improvement
- acute care
- adverse drug
- newly diagnosed
- ejection fraction
- chronic kidney disease
- primary care
- peritoneal dialysis
- staphylococcus aureus
- risk factors
- gene expression
- single cell
- clinical practice
- rectal cancer
- biofilm formation
- copy number
- risk assessment
- methicillin resistant staphylococcus aureus