Mechanisms underlying the cardiometabolic protective effect of walnut consumption in obese people: A cross-over, randomized, double-blind, controlled inpatient physiology study.
Tuccinardi DarioOlivia M FarrJagriti UpadhyaySabrina M OussaadaMaria I KlapaMarco CandelaSimone RampelliSylvain LehouxIolanda LázaroAleix Sala-VilaPatrizia BrigidiRichard D CummingsChristos S MantzorosPublished in: Diabetes, obesity & metabolism (2019)
These data provide a more comprehensive mechanistic perspective of the effect of dietary walnut consumption on cardiometabolic variables. Lipidomic and lipid nuclear magnetic resonance spectroscopy analysis showed an early but significant reduction in ceramides and other atherogenic lipids with walnut consumption, which may explain the longer-term benefits of walnuts or other nuts on insulin resistance, cardiovascular risk and mortality.
Keyphrases
- double blind
- placebo controlled
- insulin resistance
- adipose tissue
- type diabetes
- phase iii
- clinical trial
- metabolic syndrome
- phase ii
- open label
- palliative care
- mental health
- preterm infants
- weight loss
- fatty acid
- skeletal muscle
- risk factors
- cardiovascular events
- electronic health record
- high fat diet
- coronary artery disease
- study protocol
- gestational age
- obese patients
- machine learning
- preterm birth
- artificial intelligence
- glycemic control
- acute care