Treatment Options in AF Patients with Cancer; Focus on Catheter Ablation.
Silvia GaribaldiMichela ChiancaIacopo FabianiMichele EmdinMarcello PiacentiClaudio PassinoAlberto AimoAntonella FedeleCarlo Maria CipollaDaniela Maria CardinalePublished in: Journal of clinical medicine (2022)
Longer life expectancy along with advancements in cancer and atrial fibrillation (AF) therapies and treatment strategies have led to an increase in the number of individuals with both diseases. As a result, the complicated management of these patients has become crucial, necessitating individualised treatment that considers the bi-directional relationship between these two diseases. On the one hand, giving appropriate pharmaceutical therapy is exceptionally difficult, considering the recognised thromboembolic risk posed by AF and malignancy, as well as the haemorrhagic risk posed by cancer. The alternative pulmonary vein isolation (PVI) ablation, on the other hand, has been inadequately explored in the cancer patient population; there is yet inadequate data to allow the clinician to unambiguously select patients that can undertake this therapeutic intervention. The goal of this review is to compile the most valuable data and supporting evidence about the characteristics, care, and therapy of cancer patients with AF. Specifically, we will evaluate the pharmaceutical options for a proper anticoagulant therapy, as well as the feasibility and safety of PVI in this population.
Keyphrases
- atrial fibrillation
- catheter ablation
- papillary thyroid
- end stage renal disease
- left atrial
- squamous cell
- left atrial appendage
- direct oral anticoagulants
- chronic kidney disease
- ejection fraction
- newly diagnosed
- oral anticoagulants
- healthcare
- peritoneal dialysis
- randomized controlled trial
- heart failure
- stem cells
- prognostic factors
- machine learning
- left ventricular
- venous thromboembolism
- palliative care
- combination therapy
- deep learning