Amidation, Esterification, and Thioesterification of a Carboxyl-Functionalized Covalent Organic Framework.
Lei GuoShang JiaChristian S DiercksXuejing YangSultan A AlshmimriOmar M YaghiPublished in: Angewandte Chemie (International ed. in English) (2019)
Three new post-synthetic modification reactions, namely amidation, esterification, and thioesterification, were demonstrated on a novel highly crystalline two-dimensional covalent organic framework (COF), COF-616, bearing pre-installed carboxyl groups. The strategy can be used to introduce a large variety of functional groups into COFs and the modifications can be carried out under mild reaction conditions, with high yields, and an easy work-up protocol. As a proof of concept, various chelating functionalities were successfully incorporated into COF-616 to yield a family of adsorbents for efficient removal of several contaminants in the water.