Telomere Length Declines in Persons With Human Immunodeficiency Virus Before Antiretroviral Therapy Start but Not After Viral Suppression: A Longitudinal Study Over >17 Years.
Isabella C SchoepfChristian W ThorballBruno LedergerberNeeltje A KootstraPeter ReissMarieke RaffenbergTanja EngelDominique L BraunBarbara HasseChristine ThurnheerCatia MarzoliniMarco SeneghiniEnos BernasconiMatthias CavassiniHélène BuvelotJosé R ArribasRoger D KouyosJacques FellayHuldrych F GünthardPhilip E TarrPublished in: The Journal of infectious diseases (2022)
In PWH, TL is associated with an individual PRS. Telomere length declined significantly during untreated chronic HIV infection, but no TL change occurred during suppressive ART.