Interpreting single-cell messages in normal and aberrant hematopoiesis with the Cell Marker Accordion.

We developed the Cell Marker Accordion, a user-friendly platform to annotate and interpret single- cell data in normal and aberrant hematopoiesis. We a) significantly improve in annotation accuracy; b) provide detailed information on genes that influence annotation outcomes; c) identify disease- critical cells, pathological processes and potential expression biomarkers in different contexts.