Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease.

Qi GuoLingyan PingEric B DammerLuming YinKaiming XuAnantharaman ShantaramanEdward J FoxTodd E GoldeErik C B JohnsonBlaine R RobertsJames J LahAllan I LeveyNicholas T Seyfried

Published in: Research square (2024)

These findings support the utility of a heparin-affinity approach for enriching amyloid-associated proteins, as well as a wide spectrum of plasma biomarkers that reflect pathological changes in the AD brain.

Keyphrases

venous thromboembolism
growth factor
cognitive decline
white matter
resting state
functional connectivity
brain injury
subarachnoid hemorrhage