Skeletal muscle healing by M1-like macrophages produced by transient expression of exogenous GM-CSF.
Leonardo MartinsCamila Congentino GalloTâmisa Seeko Bandeira HondaPatrícia Terra AlvesRoberta Sessa StilhanoDaniela Santoro RosaTimothy Jon KohSang Won HanPublished in: Stem cell research & therapy (2020)
Collectively, our data show that increasing the number of M1-like macrophages immediately after traumatic muscle injury promotes muscle recovery with less fibrosis, and this can be achieved by the transient expression of GM-CSF.