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Shotgun metagenomics reveals an enrichment of potentially cross-reactive bacterial epitopes in ankylosing spondylitis patients, as well as the effects of TNFi therapy upon microbiome composition.

Jian YinPeter Richard SternesMingbang WangJing SongMark MorrisonTing LiLing ZhouXin WuFusheng HeJian ZhuMatthew A BrownHuji Xu
Published in: Annals of the rheumatic diseases (2019)
These findings emphasise the key role that the gut microbiome plays in driving the pathogenesis of AS and highlight potential therapeutic and/or preventative targets.
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