Matthew A Brown

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 32

Top Venues

Annals of the rheumatic diseases

Nature communications

Nature reviews. Rheumatology

RMD open

Guy's and St Thomas' NHS Foundation Trust

University of Sydney (BSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Guy's and St Thomas' NHS Foundation Trust

United Kingdom

Director, Biomedical Research Centre :: Biomedical Research Centre

Queensland University of Technology Feb 29 2016 - Oct 04 2019

Australia

Director of Genomics :: Institute of Health and Biomedical Innovation

National Health and Medical Research Council

Australia

Senior Principal Research Fellow

Wenzhou Medical University First Affiliated Hospital

China

Honorary Professor

Queensland Brain Institute

Australia

Affiliate Professor

Second Military Medical University

China

Honorary Professor

University of Oxford

United Kingdom

Honorary Professor

University of Oxford

United Kingdom

Visiting Senior Research Fellow :: Nuffield Department of Orthopaedic Surgery

University of Oxford

United Kingdom

Professor of Musculoskeletal Sciences

Nuffield Orthopaedic Centre

United Kingdom

• Deputy Director, Institute of Musculoskeletal Sciences :: Botnar Research Centre

University of Oxford

United Kingdom

O’Connor Fellow :: St Peter's College

Wellcome Trust Centre for Human Genetics

United Kingdom

Arthritis Research Campaign Senior Research Fellow

University of Oxford

United Kingdom

Clinical Reader in Musculoskeletal Sciences

University of Oxford

United Kingdom

Research Lecturer

Wellcome Trust Centre for Human Genetics

United Kingdom

Arthritis Research Campaign Clinician Scientist Fellow

Wellcome Trust Centre for Human Genetics

United Kingdom

Arthritis and Rheumatism Council Clinical Research Fellow

John Radcliffe Hospital

United Kingdom

Research Fellow and Michael Mason Fellow :: Nuffield Department of Clinical Medicine, Institute of Molecular Medicine,

Royal North Shore Hospital

Australia

• Senior Rheumatology Registrar

Cumberland College of Health Sciences

Australia

Visiting Lecturer in Bone Disorders

Prince Henry and Prince of Wales Hospital

Australia

Senior Rheumatology Registrar

Concord Repatriation General Hospital

Australia

Senior Rheumatology Registrar

Concord Repatriation General Hospital

Australia

Senior Resident

Concord Repatriation General Hospital

Australia

Junior Resident

Concord Repatriation General Hospital

Australia

Intern

Education History

University of Sydney

Australia

BSC :: Medicine

Publications

Matthew A Brown, Martin Rudwaleit, Floris A van Gaalen, Nigil Haroon, Lianne S Gensler, Carmen Fleurinck, Alexander Marten, Ute Massow, Natasha de Peyrecave, Thomas Vaux, Katy White, Atul A Deodhar, Irene van der Horst-Bruinsma
Low uveitis rates in patients with axial spondyloarthritis treated with bimekizumab: pooled results from phase 2b/3 trials. Annals of the rheumatic diseases (2024)
Matthew A Brown, Martin Rudwaleit, Floris A van Gaalen, Nigil Haroon, Lianne S Gensler, Carmen Fleurinck, Alexander Marten, Ute Massow, Natasha de Peyrecave, Thomas Vaux, Katy White, Atul A Deodhar, Irene van der Horst-Bruinsma
Low uveitis rates in patients with axial spondyloarthritis treated with bimekizumab: pooled results from phase 2b/3 trials. Annals of the rheumatic diseases (2024)
Shadi Basyuni, Laura Heskin, Andrea Degasperi, Daniella Black, Gene Ching Chiek Koh, Lucia Chmelova, Giuseppe Rinaldi, Steven Bell, Louise Grybowicz, Greg Elgar, Yasin Memari, Pauline Robbe, Zoya Kingsbury, Carlos Caldas, Jean E Abraham, Anna Schuh, Louise Jones, null null, null null, Marc Tischkowitz, Matthew A Brown, Helen R Davies, Serena Nik-Zainal
Large-scale analysis of whole genome sequencing data from formalin-fixed paraffin-embedded cancer specimens demonstrates preservation of clinical utility. Nature communications 15 (1) (2024)
Zhixiu Li, Mohammad Kazim Khan, Sjef M van der Linden, Bjorn Winkens, Peter M Villiger, Heinz Baumberger, Hermine van Zandwijk, Muhammad Asim Khan, Matthew A Brown
HLA-B27, axial spondyloarthritis and survival. Annals of the rheumatic diseases (2023)
Katie Bechman, Emma S Cook, Nick Dand, Zenas Zee Ngai Yiu, Teresa Tsakok, Freya Meynell, Bolaji Coker, Alexandra Vincent, Herve Bachelez, Ines Barbosa, Matthew A Brown, Francesca Capon, Claudia R Contreras, Claudia De La Cruz, Paola Di Meglio, Paolo Gisondi, Denis Jullien, Jade Kelly, Jo Lydie Wilfried Lambert, Camille Lancelot, Sinéad M Langan, Kayleigh J Mason, Helen McAteer, Lucy Moorhead, Luigi Naldi, Katherine Jones, Lluis L Puig, Phyllis I Spuls, Tiago Torres, Dominic Urmston, Amber Vesty, Richard Bruce Warren, Hoseah Waweru, John Weinman, Christopher Ernest Maitland Griffiths, Jonathan N W N Barker, Catherine H Smith, James B Galloway, Satveer K Mahil, null null
Vaccine hesitancy and access to psoriasis care during the COVID-19 pandemic: findings from a global patient-reported cross-sectional survey. The British journal of dermatology 187 (2) (2022)
Jose Garrido-Mesa, Matthew A Brown
T cell Repertoire Profiling and the Mechanism by which HLA-B27 Causes Ankylosing Spondylitis. Current rheumatology reports 24 (12) (2022)
Sjef M van der Linden, Muhammad Asim Khan, Zhixiu Li, Heinz Baumberger, Hermine van Zandwijk, Kazim Khan, Peter M Villiger, Matthew A Brown
Factors predicting axial spondyloarthritis among first-degree relatives of probands with ankylosing spondylitis: a family study spanning 35 years. Annals of the rheumatic diseases 81 (6) (2022)
Lauren K Ridley, Mark C Hwang, John D Reveille, Lianne S Gensler, Mariko L Ishimori, Matthew A Brown, Mohammad Hossein Rahbar, Amirali Tahanan, Michael M Ward, Michael H Weisman, Thomas J Learch
Why Do Some Patients Have Severe Sacroiliac Disease But No Syndesmophytes in Ankylosing Spondylitis? Data From a Nested Case-Control Study. The Journal of rheumatology (2022)
Matthew A Brown, Christopher Wigley, Susan Walker, Deborah Lancaster, Augusto Rendon, Richard H Scott
Re: Best et al., 'Unlocking the potential of the UK 100,000 Genomes Project - Lessons learned from analysis of the "Congenital malformations caused by ciliopathies" cohort'. American journal of medical genetics. Part A 188 (11) (2022)
Xiu-Feng Huang, Matthew A Brown
Progress in the genetics of uveitis. Genes and immunity 23 (2) (2022)
Sjef M van der Linden, Muhammad Asim Khan, Zhixiu Li, Heinz Baumberger, Hermine van Zandwijk, Mohammad Kazim Khan, Peter M Villiger, Matthew A Brown
Recurrence of axial spondyloarthritis among first-degree relatives in a prospective 35-year-follow-up family study. RMD open 8 (2) (2022)
Zhixiu Li, Sjef M van der Linden, Muhammad Asim Khan, Heinz Baumberger, Hermine van Zandwijk, Mohammad Kazim Khan, Peter M Villiger, Matthew A Brown
Heterogeneity of axial spondyloarthritis: genetics, sex and structural damage matter. RMD open 8 (1) (2022)
Mark C Hwang, Min Jae Lee, Lianne S Gensler, Matthew A Brown, Amirali Tahanan, Mohammad H Rahbar, Theresa Hunter, Mingyan Shan, Mariko L Ishimori, John D Reveille, Michael H Weisman, Thomas J Learch, null null
Identifying Trajectories of Radiographic Spinal Disease in Ankylosing Spondylitis: A 15-year follow up study of the PSOAS Cohort. Rheumatology (Oxford, England) (2021)
Marialbert Acosta-Herrera, Martin Kerick, Elena Lopéz-Isac, Shervin Assassi, Lorenzo Beretta, Carmen Pilar Simeón-Aznar, Norberto Ortego-Centeno, null null, Susanna M Proudman, null null, Nicolas Hunzelmann, Gianluca Moroncini, Jeska K de Vries-Bouwstra, Gisela Orozco, Richard B Warren, Ariane L Herrick, Chikashi Terao, Yannick Allanore, Matthew A Brown, Timothy Rdj Radstake, Carmen Fonseca, Christopher P Denton, Maureen D Mayes, Javier Martín
Comprehensive analysis of the major histocompatibility complex in systemic sclerosis identifies differential HLA associations by clinical and serological subtypes. Annals of the rheumatic diseases (2021)
Giuliana Guggino, Daniele Mauro, Aroldo Rizzo, Riccardo Alessandro, Stefania Raimondo, Anne-Sophie Bergot, M Arifur Rahman, Jonathan J Ellis, Simon Milling, Rik Ju Lories, Dirk Elewaut, Matthew A Brown, Ranjeny Thomas, Francesco Ciccia
Inflammasome Activation in Ankylosing Spondylitis Is Associated With Gut Dysbiosis. Arthritis & rheumatology (Hoboken, N.J.) 73 (7) (2021)
Matthew A Brown, Daniel Aletaha
Genetic risk scores in inflammatory arthritis: a new era? Nature reviews. Rheumatology 16 (10) (2021)
Zhixiu Li, Xin Wu, Paul J Leo, Erika De Guzman, Nurullah Akkoc, Maxime Breban, Gary John Macfarlane, Mahdi Mahmoudi, Helena Marzo-Ortega, Lisa K Anderson, Lawrie Wheeler, Chung-Tei Chou, Andrew A Harrison, Simon M Stebbings, Gareth T Jones, So-Young Bang, Geng Wang, Ahmadreza Jamshidi, Elham Farhadi, Jing Song, Li Lin, Mengmeng Li, James Cheng Chung Wei, Nicholas G Martin, Margaret J Wright, Min Jae Lee, Yuqin Wang, Jian Zhan, Jin-San Zhang, Xiaobing Wang, Zi-Bing Jin, Michael H Weisman, Lianne S Gensler, Michael M Ward, Mohammad Hossein Rahbar, Laura Diekman, Tae Hwan Kim, John D Reveille, Bryan Paul Wordsworth, Huji Xu, Matthew A Brown, null null
Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis. Annals of the rheumatic diseases 80 (9) (2021)
Daniele Mauro, Ranjeny Thomas, Giuliana Guggino, Rik Lories, Matthew A Brown, Francesco Ciccia
Ankylosing spondylitis: an autoimmune or autoinflammatory disease? Nature reviews. Rheumatology 17 (7) (2021)
Joanne M Hildebrand, Maria Kauppi, Ian J Majewski, Zikou Liu, Allison J Cox, Sanae Miyake, Emma J Petrie, Michael A Silk, Zhixiu Li, Maria C Tanzer, Gabriela Brumatti, Samuel N Young, Cathrine Hall, Sarah E Garnish, Jason Corbin, Michael D Stutz, Ladina Di Rago, Pradnya Gangatirkar, Emma C Josefsson, Kristin Rigbye, Holly Anderton, James A Rickard, Anne Tripaydonis, Julie M Sheridan, Thomas S Scerri, Victoria E Jackson, Peter E Czabotar, Jian-Guo Zhang, Leila Varghese, Cody C Allison, Marc Pellegrini, Gillian M Tannahill, Esme C Hatchell, Tracy A Willson, Dina Stockwell, Carolyn A de Graaf, Janelle Collinge, Adrienne Hilton, Natasha Silke, Sukhdeep K Spall, Diep Chau, Vicki Athanasopoulos, Donald Metcalf, Ronald M Laxer, Alexander G Bassuk, Benjamin W Darbro, Maria A Fiatarone Singh, Nicole Vlahovich, David Hughes, Maria Kozlovskaia, David Benjamin Ascher, Klaus Warnatz, Nils Venhoff, Jens Thiel, Christine Biben, Stefan Blum, John Reveille, Michael S Hildebrand, Carola G Vinuesa, Pamela A McCombe, Matthew A Brown, Benjamin T Kile, Catriona A Mclean, Melanie Bahlo, Seth L Masters, Hiroyasu Nakano, Polly J Ferguson, James G Murphy, Warren S Alexander, John Silke
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction. Nature communications 11 (1) (2020)
Marta F Nabais, Tian Lin, Beben Benyamin, Kelly Louise Williams, Fleur C Garton, Anna A E Vinkhuyzen, Futao Zhang, Costanza L Vallerga, Restuadi Restuadi, Anna Freydenzon, Ramona A J Zwamborn, Paul J Hop, Matthew R Robinson, Jacob Gratten, Peter M Visscher, Eilis J Hannon, Jonathan Mill, Matthew A Brown, Nigel G Laing, Karen A Mather, Perminder Singh Sachdev, Shyuan T Ngo, Frederik J Steyn, Leanne Wallace, Anjali K Henders, Merrilee Needham, Jan H Veldink, Susan Mathers, Garth Nicholson, Dominic B Rowe, Robert D Henderson, Pamela A McCombe, Roger Pamphlett, Jian Yang, Ian P Blair, Allan F McRae, Naomi R Wray
Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. NPJ genomic medicine 5 (2020)
Mark C Hwang, Min Jae Lee, Lianne S Gensler, Michael M Ward, Matthew A Brown, Seth Eisen, Thomas J Learch, Amirali Tahanan, Mohammad H Rahbar, Mariko L Ishimori, Michael H Weisman, John D Reveille
Longitudinal associations between depressive symptoms and clinical factors in ankylosing spondylitis patients: analysis from an observational cohort. Rheumatology international 40 (7) (2020)
Abdulla Watad, Hannah Rowe, Tobias Russell, Qiao Zhou, Lisa K Anderson, Almas Khan, Robert Dunsmuir, Peter Loughenbury, Vishal Borse, Abhay Rao, Peter A Millner, Nicola Luigi Bragazzi, Howard Amital, Richard Cuhtbert, Miriam Wittmann, Kassem Sharif, Tony Kenna, Matthew A Brown, Darren J Newton, Charlie Bridgewood, Dennis G McGonagle
Normal human enthesis harbours conventional CD4+ and CD8+ T cells with regulatory features and inducible IL-17A and TNF expression. Annals of the rheumatic diseases 79 (8) (2020)
Melissa M Gresle, Margaret A Jordan, Jim Stankovich, Tim Spelman, Laura J Johnson, Louise Laverick, Alison Hamlett, Letitia D Smith, Vilija G Jokubaitis, Josephine Baker, Jodi Haartsen, Bruce Taylor, Jac C Charlesworth, Melanie Bahlo, Terence P Speed, Matthew A Brown, Judith Field, Alan G Baxter, Helmut Butzkueven
Multiple sclerosis risk variants regulate gene expression in innate and adaptive immune cells. Life science alliance 3 (7) (2020)
Matthew A Brown, Zhixiu Li, Kim-Anh Lê Cao
Biomarker development for axial spondyloarthritis. Nature reviews. Rheumatology 16 (8) (2020)
Sina Rostami, Mari Hoff, Matthew A Brown, Kristian Hveem, Oddgeir L Holmen, Lars G Fritsche, Vibeke Videm
Prediction of Ankylosing Spondylitis in the HUNT Study by a Genetic Risk Score Combining 110 Single-nucleotide Polymorphisms of Genome-wide Significance. The Journal of rheumatology 47 (2) (2019)
David L Duffy, Gu Zhu, Xin Li, Marianna Sanna, Mark M Iles, Leonie C Jacobs, David M Evans, Seyhan Yazar, Jonathan Beesley, Matthew H Law, Peter Kraft, Alessia Visconti, John C Taylor, Fan Liu, Margaret J Wright, Anjali K Henders, Lisa Bowdler, Dan Glass, Mohammad Arfan Ikram, André G Uitterlinden, Pamela A Madden, Andrew C Heath, Elliot C Nelson, Adéle C Green, Stephen J Chanock, Jennifer H Barrett, Matthew A Brown, Nicholas K Hayward, Stuart Macgregor, Richard A Sturm, Alex W Hewitt, null null, Manfred Kayser, David J Hunter, Julia A Newton Bishop, Timothy D Spector, Grant W Montgomery, David A Mackey, George Davey Smith, Tamar E Nijsten, D Timothy Timothy Bishop, Veronique Bataille, Mario Falchi, Jiali Han, Nicholas G Martin
Publisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nature communications 10 (1) (2019)
Lusi Ye, Yuncai Liu, Qinqin Xiao, Ledan Dong, Caiyun Wen, Zhang Zhang, Mengmeng Jin, Matthew A Brown, Dan Chen
MRI compared with low-dose CT scanning in the diagnosis of axial spondyloarthritis. Clinical rheumatology 39 (4) (2019)
Elena López-Isac, Marialbert Acosta-Herrera, Martin Kerick, Shervin Assassi, Ansuman T Satpathy, Jeffrey Granja, Maxwell R Mumbach, Lorenzo Beretta, Carmen P Simeón, Patricia Carreira, Norberto Ortego-Centeno, Ivan Castellvi, Lara Bossini-Castillo, Francisco David Carmona, Gisela Orozco, Nicolas Hunzelmann, Jörg H W Distler, Andre Franke, Claudio Lunardi, Gianluca Moroncini, Armando Gabrielli, Jeska de Vries-Bouwstra, Cisca Wijmenga, Bobby P C Koeleman, Annika Nordin, Leonid Padyukov, Anna-Maria Hoffmann-Vold, Benedicte Lie, null null, Susanna Proudman, Wendy Stevens, Mandana Nikpour, null null, Timothy J Vyse, Ariane L Herrick, Jane Worthington, Christopher P Denton, Yannick Allanore, Matthew A Brown, Timothy R D J Radstake, Carmen Fonseca, Howard Y Chang, Maureen D Mayes, Javier Martin
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways. Nature communications 10 (1) (2019)
Jian Yin, Peter Richard Sternes, Mingbang Wang, Jing Song, Mark Morrison, Ting Li, Ling Zhou, Xin Wu, Fusheng He, Jian Zhu, Matthew A Brown, Huji Xu
Shotgun metagenomics reveals an enrichment of potentially cross-reactive bacterial epitopes in ankylosing spondylitis patients, as well as the effects of TNFi therapy upon microbiome composition. Annals of the rheumatic diseases 79 (1) (2019)
Jessica M Whyte, Jonathan J Ellis, Matthew A Brown, Tony J Kenna
Best practices in DNA methylation: lessons from inflammatory bowel disease, psoriasis and ankylosing spondylitis. Arthritis research & therapy 21 (1) (2019)
Rebecca L Roberts, Mary C Wallace, Andrew A Harrison, Douglas White, Nicola Dalbeth, Lisa K Stamp, Daniel Ching, John Highton, Tony R Merriman, Philip C Robinson, Matthew A Brown, Simon M Stebbings
Association of Crohn's disease-related chromosome 1q32 with ankylosing spondylitis is independent of bowel symptoms and faecal calprotectin. PeerJ 6 (2018)
David L Duffy, Gu Zhu, Xin Li, Marianna Sanna, Mark M Iles, Leonie C Jacobs, David M Evans, Seyhan Yazar, Jonathan Beesley, Matthew H Law, Peter Kraft, Alessia Visconti, John C Taylor, Fan Liu, Margaret J Wright, Anjali K Henders, Lisa Bowdler, Dan Glass, Mohammad Arfan Ikram, André G Uitterlinden, Pamela A Madden, Andrew C Heath, Elliot C Nelson, Adéle C Green, Stephen J Chanock, Jennifer H Barrett, Matthew A Brown, Nicholas K Hayward, Stuart Macgregor, Richard A Sturm, Alex W Hewitt, null null, Manfred Kayser, David J Hunter, Julia A Newton Bishop, Timothy D Spector, Grant W Montgomery, David A Mackey, George Davey Smith, Tamar E Nijsten, D Timothy Timothy Bishop, Veronique Bataille, Mario Falchi, Jiali Han, Nicholas G Martin
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nature communications 9 (1) (2018)

Matthew A Brown

Publication Activity (10 Years)

Top Topics

Top Venues