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Ubiquitin-proteasome pathway annotation in Diaphorina citri can reveal potential targets for RNAi-based pest management.

Will TankTeresa D ShippyAmanda ThateCrissy MassiminoPrashant S HosmaniMirella Flores-GonzalezLukas A MuellerWayne Brian HunterSusan J BrownTom D'EliaSurya Saha
Published in: GigaByte (Hong Kong, China) (2022)
Ubiquitination is an ATP-dependent process that targets proteins for degradation by the proteasome. Here, we annotated 15 genes from the ubiquitin-proteasome pathway in the Asian citrus psyllid, Diaphorina citri . This psyllid vector has come to prominence in the last decade owing to its role in the transmission of the devastating bacterial pathogen, Candidatus Liberibacter asiaticus ( C Las). Infection of citrus crops by this pathogen causes Huanglongbing (HLB), or citrus greening disease, and results in the eventual death of citrus trees. The identification and correct annotation of these genes in D. citri will be useful for functional genomic studies to aid the development of RNAi-based management strategies aimed at reducing the spread of HLB. Investigating the effects of C Las infection on the expression of ubiquitin-proteasome pathway genes may provide new information about the role these genes play in the acquisition and transmission of C Las by D. citri .
Keyphrases
  • genome wide
  • bioinformatics analysis
  • genome wide identification
  • small molecule
  • dna methylation
  • copy number
  • poor prognosis
  • candida albicans
  • social media