Hepatitis C virus eradication by direct-acting antivirals causes a simultaneous increase in the prevalence of fatty liver and hyper-LDL cholesterolemia without an increase in body weight.
Yoshimasa TokuchiGoki SudaNaoki KawagishiMasatsugu OharaRisako KohyaTakashi SasakiTomoka YodaOsamu MaeharaShunsuke OhnishiAkinori KuboSonoe YoshidaQingjie FuZijian YangShunichi HosodaTakashi KitagatayaKazuharu SuzukiMasato NakaiTakuya ShoMitsuteru NatsuizakaKoji OgawaNaoya SakamotoPublished in: Hepatology research : the official journal of the Japan Society of Hepatology (2023)
DAAs may cause an increased prevalence of fatty liver accompanying hyper-LDL-cholesterolemia without increased body weight. Since post-SVR liver steatosis could cause HCC, careful follow-up may be required.