Alda-1 ameliorates air embolism-induced acute lung injury.
Shu-Yu WuShi-Jye ChuShih-En TangHsin-Ping PaoWen-I LiaoPublished in: International journal of immunopathology and pharmacology (2023)
Alda-1 shows promise in mitigating AE-induced ALI, possibly through the upregulation of ALDH2 expression and suppression of the PI3K/Akt and NF-κB signaling pathways. Further research is warranted to validate these findings and to explore their translational potential in human subjects.
Keyphrases
- signaling pathway
- high glucose
- poor prognosis
- endothelial cells
- diabetic rats
- lps induced
- pi k akt
- cell proliferation
- oxidative stress
- drug induced
- lipopolysaccharide induced
- mouse model
- machine learning
- inflammatory response
- induced apoptosis
- epithelial mesenchymal transition
- toll like receptor
- artificial intelligence