The Hurdle of Access to Emerging Therapies and Potential Solutions in the Management of Dyslipidemias.
Brett Stephen MansfieldFarzahna MohamedMiriam LaroucheFrederick J RaalPublished in: Journal of clinical medicine (2024)
This review explores the many barriers to accessing lipid-lowering therapies (LLTs) for the prevention and management of atherosclerotic cardiovascular disease (ASCVD). Geographical, knowledge, and regulatory barriers significantly impede access to LLTs, exacerbating disparities in healthcare infrastructure and affordability. We highlight the importance of policy reforms, including pricing regulations and reimbursement policies, for enhancing affordability and streamlining regulatory processes. Innovative funding models, such as value-based pricing and outcome-based payment arrangements, have been recommended to make novel LLTs more accessible. Public health interventions, including community-based programs and telemedicine, can be utilized to reach underserved populations and improve medication adherence. Education and advocacy initiatives led by patient advocacy groups and healthcare providers play a crucial role in raising awareness and empowering patients. Despite the barriers to access, novel LLTs present a big opportunity to reduce the burden of ASCVD, emphasizing the need for collaborative efforts among policymakers, healthcare providers, industry stakeholders, and patient advocacy groups to address these barriers to improve access to LLTs globally.
Keyphrases
- healthcare
- public health
- cardiovascular disease
- quality improvement
- case report
- end stage renal disease
- newly diagnosed
- transcription factor
- affordable care act
- type diabetes
- prognostic factors
- global health
- health information
- physical activity
- health insurance
- risk assessment
- risk factors
- peritoneal dialysis
- patient reported
- metabolic syndrome
- human health