GIP attenuates neuronal oxidative stress by regulating glucose uptake in spinal cord injury of rat.
Beibei GuoMengwei QiXiaoqian LuoLongyu GuoMan XuYufang ZhangZhen LiMingxuan LiRonghua WuTuchen GuanMei LiuYan LiuPublished in: CNS neuroscience & therapeutics (2024)
GIP increases GLUT3 expression and promotes glucose intake in neurons, which exerts an antioxidant effect and protects neuronal cells from oxidative stress both in vitro and in vivo.
Keyphrases
- oxidative stress
- spinal cord injury
- spinal cord
- diabetic rats
- dna damage
- ischemia reperfusion injury
- induced apoptosis
- blood glucose
- poor prognosis
- cerebral ischemia
- neuropathic pain
- type diabetes
- binding protein
- heat shock
- body mass index
- physical activity
- blood pressure
- long non coding rna
- skeletal muscle
- brain injury
- adipose tissue
- anti inflammatory