Reduced midbrain raphe echogenicity in patients with fibromyalgia syndrome.
Nurcan ÜçeylerMira SchließerDimitar EvdokimovJakub RadziwonBetty FeulnerStefan UntereckerFlorian RimmeleUwe WalterPublished in: PloS one (2022)
We found reduced echogenicity of the midbrain raphe area in patients with FMS and in patients with depression and physical pain, independent of the presence or severity of pain, FMS, and depressive symptoms. Further exploration of this sonographic finding is necessary before this objective technique may enter diagnostic algorithms in FMS and depression.