Association of Structural Measurements of Brain Reserve With Motor Progression in Patients With Parkinson Disease.
Linbo WangPing WuPeter BrownWei ZhangFengtao LiuYan HanChuan-Tao ZuoWei ChengJianfeng FengPublished in: Neurology (2022)
PD patients with greater brain resources (that is, higher DBM values) had greater compensatory capacity, which was associated with slower rates of clinical progression. This knowledge could be used to stratify and monitor patients for clinical trials.
Keyphrases
- parkinson disease
- clinical trial
- end stage renal disease
- resting state
- white matter
- deep brain stimulation
- newly diagnosed
- ejection fraction
- healthcare
- chronic kidney disease
- prognostic factors
- functional connectivity
- randomized controlled trial
- multiple sclerosis
- open label
- blood brain barrier
- study protocol
- patient reported