The Impact of Drug Trials With Financial Conflict of Interests on the Meta-analyses: A Meta-epidemiological Study.
Haitong ZhaoPeijing YanHaitong ZhaoLufang FengXiajing ChuJingwen LiNan ChenKe-Hu YangXingrong LiuPublished in: International journal of health policy and management (2021)
In this meta-epidemiological study, we demonstrated that trials with FCOIs may not only influence the final outcome of MAs but may also increase the heterogeneity of results. It is suggested that all MAs fully report the FCOIs involved in evidence-based research and explore the impact of its FCOIs to better provide a more valuable reference for patients, clinicians, and policy-makers.
Keyphrases
- meta analyses
- end stage renal disease
- ejection fraction
- newly diagnosed
- healthcare
- systematic review
- chronic kidney disease
- public health
- palliative care
- prognostic factors
- peritoneal dialysis
- randomized controlled trial
- mental health
- emergency department
- single cell
- patient reported outcomes
- electronic health record