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Safety and efficacy of clonidine on postoperative vomiting and pain in pediatric ophthalmic surgery: A systematic review and meta-analysis.

Yuan-Pin HsuKaren Chia-Wen ChuChyi-Huey BaiChun-Jen HuangChiehfeng ChenChin-Wang Hsu
Published in: Paediatric anaesthesia (2019)
Compared to placebo or benzodiazepine, clonidine premedication was effective in reducing postoperative vomiting in pediatric patients undergoing ophthalmic surgery. Clonidine premedication also provided more reduction in postoperative pain when compared to placebo. The use of clonidine premedication was not associated with adverse hemodynamic events.
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