The Effect of Vasopressin and Methylprednisolone on Return of Spontaneous Circulation in Patients with In-Hospital Cardiac Arrest: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Basel AbdelazeemAhmed Khaled AwadNouraldeen ManasrahMerihan A ElbadawySoban AhmadPramod SavarapuKirellos Said AbbasArvind KunadiPublished in: American journal of cardiovascular drugs : drugs, devices, and other interventions (2022)
Among patients with in-hospital cardiac arrest, administration of vasopressin and methylprednisolone besides epinephrine is associated with increased ROSC compared with placebo and epinephrine. However, high-quality RCTs are necessary before drawing a firm conclusion regarding the efficacy of vasopressin and methylprednisolone for patients with in-hospital cardiac arrest.