hsa_circ_0000231 Promotes colorectal cancer cell growth through upregulation of CCND2 by IGF2BP3/miR-375 dual pathway.

Wei ZhangBo WangYilin LinYang YangZhen ZhangQuan WangHaoran ZhangKewei JiangYingjiang YeShan WangZhanlong Shen

Published in: Cancer cell international (2022)

The findings suggested that hsa_circ_0000231 facilitated CRC progression by sponging miR-375 or binding to IGF2BP3 to modulate CCND2, implying that hsa_circ_0000231 might be a potential new diagnostic and therapeutic biomarker of CRC.

Keyphrases

cell proliferation
long non coding rna
pi k akt
long noncoding rna
poor prognosis
binding protein
signaling pathway
risk assessment