Effect of behavioral weight-loss program on biomarkers of cardiometabolic disease risk: Heart Health Study randomized trial.
Katherine A CollinsWilliam E KrausRenee J RogersElizabeth R HauserWei LangRong JiangErik B SchelbertKim M HuffmanJohn M JakicicPublished in: Obesity (Silver Spring, Md.) (2023)
All intervention groups prompted a notable beneficial change among biomarkers of insulin resistance and cardiometabolic health. However, the addition of at least moderate-intensity physical activity to a diet-only intervention did not provide any additional benefit. These findings highlight that an average weight loss of approximately 10% profoundly impacts biomarkers of insulin resistance and cardiometabolic disease in adults with overweight or obesity.
Keyphrases
- weight loss
- insulin resistance
- bariatric surgery
- roux en y gastric bypass
- physical activity
- gastric bypass
- randomized controlled trial
- healthcare
- public health
- glycemic control
- metabolic syndrome
- adipose tissue
- high intensity
- mental health
- high fat diet
- type diabetes
- weight gain
- high fat diet induced
- polycystic ovary syndrome
- skeletal muscle
- health information
- obese patients
- body mass index
- human health
- risk assessment
- sleep quality