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Intragenic amplification of PAX5: a novel subgroup in B-cell precursor acute lymphoblastic leukemia?

Claire SchwabKarin NebralLucy ChiltonCristina LeschiEsmé WaandersJudith M BoerMarkéta ŽaliováRosemary SuttonIngegerd Ivanov ÖfverholmKentaro OhkiYuka YamashitaStefanie Groeneveld-KrentzEva FroňkováMarleen BakkusJoelle TchindaThayana da Conceição BarbosaGrazia FazioWojciech MlynarskiAgata PastorczakGiovanni CazzanigaMaria S Pombo-de-OliveiraJan TrkaRenate Kirschner-SchwabeToshihiko ImamuraGisela BarbanyMartin StanullaAndishe AttarbaschiRenate Panzer-GrümayerRoland P KuiperMonique L den BoerHélène CaveAnthony V MoormanChristine J HarrisonSabine Strehl
Published in: Blood advances (2017)
Intragenic PAX5 amplification defines a novel, relapse-prone subtype of B-cell precursor acute lymphoblastic leukemia with a poor outcome.
Keyphrases
  • acute lymphoblastic leukemia
  • nucleic acid
  • allogeneic hematopoietic stem cell transplantation
  • label free
  • randomized controlled trial
  • phase iii