Puberty and sex in pediatric thyroid cancer: could expression of estrogen and progesterone receptors affect prognosis?

Julia Ramalho Amalio da Silva BrederPaulo Alonso Garcia AlvesMario Lucio AraújoBarbara PiresPriscila ValverdeDaniel Alves BulzicoFernanda Andrade AcciolyRossana CorboMario VaismanFernanda Vaisman

Published in: European thyroid journal (2022)

Our study showed that the completion of puberty correlated best with the clinical behaviour of pediatric thyroid cancer. It was also shown that postpubertal patients have a less aggressive initial presentation and better outcomes. However, this observation could not be explained by the expression of estrogen and progesterone receptors in the primary tumors.

Keyphrases

estrogen receptor
poor prognosis
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
type diabetes
metabolic syndrome
case report
patient reported
glycemic control