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Relationship between SIRT1 gene expression level and disease in age-related cataract cases

Nihat Buğra AğaoğluNuray VarolSaliha Handan YıldızCem KaraosmanoğluRahmi DumanMüjgan Özdemir ErdoğanMustafa Solak
Published in: Turkish journal of medical sciences (2019)
The expression level of SIRT1 plays a vital role in the development of age-related cataract and it can be used as a biomarker. Thus, SIRT1 inhibitors can be used in the treatment of age-related cataract disease.
Keyphrases
  • gene expression
  • oxidative stress
  • ischemia reperfusion injury
  • poor prognosis
  • dna methylation
  • cataract surgery
  • long non coding rna
  • combination therapy