Identification of the Aedes aegypti nAChR gene family and molecular target of spinosad.

Jianqiang LanZihe WangZhaohui ChenLei ZhangJianguo ZhaoQingfeng GuanChenghong LiaoNannan LiuQian Han

Published in: Pest management science (2020)

CRISPR/Cas9 introduced truncated Aaeα6 receptor in Ae. aegypti resulted in an increased level of resistance to spinosad, suggesting that the conserved nAChR α6 subunit is the target for spinosad insecticide. © 2020 Society of Chemical Industry.

Keyphrases

aedes aegypti
crispr cas
zika virus
dengue virus
genome editing
transcription factor
single molecule
bioinformatics analysis
protein kinase