Decreased Tertiary Lymphoid Structures in Lung Adenocarcinomas with ALK Rearrangements.

Yi ZouJing ZhaoFengbo HuangXueping XiangYang Xia

Published in: Journal of clinical medicine (2022)

ALK+ LUAD harbored a cold TIME featured by decreased TLS formation, which closely correlated to tumor progression and might contribute to the poor efficiency of ICIs.

Keyphrases

advanced non small cell lung cancer
poor prognosis
high resolution
epidermal growth factor receptor
tyrosine kinase