Lipid-Associated Macrophages Are Induced by Cancer-Associated Fibroblasts and Mediate Immune Suppression in Breast Cancer.
Eleonora TimperiPaul GueguenMartina MolgoraIlaria MagagnaYann KiefferSylvain BaulandePhilemon SirvenLaura G BaudrinSylvain BaulandeAndré NicolasGabriel ChampenoisDidier MeseureAnne-Vincent SalomonAnne TardivonEnora LaasVassili SoumelisMarco ColonnaFatima Mechta-GrigoriouSebastian AmigorenaEmanuela RomanoPublished in: Cancer research (2022)
This work identifies a novel lipid-associated macrophage subpopulation with immune suppressive functions, offering new leads for therapeutic interventions in triple-negative breast cancer.