The Prognostic Value of Cancer Stem Cell Markers (Notch1, ALDH1, and CD44) in Primary Colorectal Carcinoma.

Salem Youssef MohamedRanda Mohamed KafMona Mostafa AhmedAmira ElwanHassan R AshourAmr Ibrahim

Published in: Journal of gastrointestinal cancer (2020)

Expression of stem cell markers ALDH1, Notch1, and CD44 correlates with poor prognosis in a CRC and represents an independent prognostic factor. They are associated with a feature of epithelial-mesenchymal transition evidenced by their association with high tumor burden.

Keyphrases

poor prognosis
prognostic factors
epithelial mesenchymal transition
long non coding rna
cancer stem cells
stem cells
cell proliferation
machine learning
nk cells
transforming growth factor
signaling pathway
deep learning
risk factors
bone marrow
neural network