The role of rs242941, rs1876828, rs242939 and rs110402 polymorphisms of CRHR1 gene and the depression: systematic review and meta-analysis.

Yazmín Hernández-DíazThelma Beatriz González-CastroIsela Esther Juárez-RojopCarlos Alfonso Tovilla-ZárateMaría Lilia López-NarváezAlma Delia Genis-MendozaAna FresanHumberto Nicolini

Published in: Genes & genomics (2021)

Our meta-analysis shows that some variants of the CRHR1 gene (rs242941, rs1876828 and rs242939) might confer susceptibility to depression. Further studies with larger sample sizes need to be conducted.

Keyphrases

systematic review
copy number
depressive symptoms
genome wide
randomized controlled trial
gene expression
sleep quality
physical activity
case control
genome wide identification