The effectiveness of coronary computed tomography angiography and functional testing for the diagnosis of obstructive coronary artery disease: results from the individual patient data Collaborative Meta-Analysis of Cardiac CT (COME-CCT).
Peter SchlattmannViktoria WieskeKeno K BressemTheresa GötzGeorg M SchuetzDaniele AndreiniGianluca PontoneHatem AlkadhiJörg HausleiterElke ZimmermannBernhard GerberAbbas A ShabestariMatthijs F L MeijsAkira SatoKristian A ØvrehusShona M M JenkinsJuhani KnuutiAshraf HamdanBjørn A HalvorsenVladimir Mendoza-RodriguezJohannes RixeYung-Liang WanChristoph LangerSebastian LeschkaEugenio MartuscelliSaid GhostineJean-Claude TardifAlejandra Rodríguez SánchezRobert HaaseMarc DeweyPublished in: Insights into imaging (2024)
Coronary computed tomography angiography showed significantly better diagnostic performance (p < 0.0001) for diagnosis of coronary artery disease compared to exercise-ECG and SPECT. The positive predictive value of coronary computed tomography angiography was ≥ 50% in patients with a clinical pretest probability of at least 10%, for ECG ≥ 40%, and for SPECT 28%. Coronary computed tomography angiography reliably excluded obstructive coronary artery disease with a post-test probability of below 15% in patients with a pretest probability of up to 74%.
Keyphrases
- coronary artery disease
- coronary artery
- image quality
- systematic review
- percutaneous coronary intervention
- cardiovascular events
- coronary artery bypass grafting
- randomized controlled trial
- aortic stenosis
- computed tomography
- heart rate variability
- heart rate
- type diabetes
- pet ct
- case report
- electronic health record
- magnetic resonance
- quality improvement
- machine learning
- meta analyses
- body composition
- artificial intelligence