Optimized dual-time-window protocols for quantitative [18F]flutemetamol and [18F]florbetaben PET studies.
Fiona HeemanMaqsood YaqubIsadora Lopes AlvesKerstin HeurlingJohannes BerkhofJuan Domingo Gispert LópezSantiago BullichChristopher FoleyAdriaan A Lammertsmanull nullPublished in: EJNMMI research (2019)
The length of the interval inversely correlates with the accuracy of the BPND estimates. Consequently, a dual-time-window protocol of 0-30 and 90-110 min (=maximum of 60 min interval) allows for accurate estimation of BPND values for both tracers. [18F]flutemetamol: EudraCT 2007-000784-19, registered 8 February 2007, [18F]florbetaben: EudraCT 2006-003882-15, registered 2006.