Mixing Matrix-corrected Whole-body Pharmacokinetic Modeling Using Longitudinal Micro-computed Tomography and Fluorescence-mediated Tomography.

Simin ZuoWa'el Al RawashdehStefanie RosenhainZuzanna MagnuskaYamoah Grace GyamfuahFabian KießlingFelix Gremse

Published in: Molecular imaging and biology (2021)

The mixing matrix correction improves pharmacokinetic modeling and thus enables a more accurate assessment of the biodistribution of fluorescently labeled pharmaceuticals by μCT-FMT.

Keyphrases

computed tomography
dual energy
positron emission tomography
pet imaging
image quality
contrast enhanced
magnetic resonance imaging
high resolution
single molecule
cross sectional
magnetic resonance
energy transfer
pet ct
quantum dots