Association Between Body Weight and Telomere Length Is Predominantly Mediated Through C-Reactive Protein.
Xiao GaoShengxu LiShiqiu DongJiaqi LiYinkun YanTao ZhangWei ChenPublished in: The Journal of clinical endocrinology and metabolism (2021)
These results suggest that the inverse BMI-LTL association is partly mediated by obesity-induced inflammation. The significant direct effect of BMI on LTL with removal of the mediation effect through CRP indicates that obesity is associated with LTL attrition also through other noninflammatory mechanisms.