The Effects of Human Immunodeficiency Virus Type 1 (HIV-1) Antigen-Expanded Specific T-Cell Therapy and Vorinostat on Persistent HIV-1 Infection in People With HIV on Antiretroviral Therapy.
Cynthia L GayPatrick J HanleyShane D FalcinelliJoAnn D KurucSusan M PedersenJennifer KirchherrSamuel L M RainesCecilia M MottaChris LazarskiPamela ChanskyJay TannaAbeer ShibliAnushree DatarChase D McCannUluhan SiliRuian KeJoseph J EronNancie ArchinNilu GoonetillekeCatherine M BollardDavid M MargolisPublished in: The Journal of infectious diseases (2024)
These modest effects provide support for the strategy of HIV latency reversal and reservoir clearance, but more effective interventions are needed to yield the profound depletion of persistent HIV likely to yield clinical benefit. Clinical Trials Registration. NCT03212989.