Spatially Resolved Metabolites in Stable and Unstable Human Atherosclerotic Plaques Identified by Mass Spectrometry Imaging.
Erin H SeeleyZhipeng LiuShuai YuanChad StroopeElizabeth CockerhamNabil A RashdanLuisa DelgadilloAlexandra C FinneyDhananjay KumarSandeep DasBabak RazaniWanqing LiuJames TraylorAnthony Wayne OrrOren RomChristopher B PattilloArif YurdagulPublished in: Arteriosclerosis, thrombosis, and vascular biology (2023)
Our work here represents the first step to defining an atlas of metabolic pathways involved in plaque destabilization in human atherosclerosis. We anticipate this will be a valuable resource and open new avenues of research in cardiovascular disease.