Retrograde cholesterol transport in the human Caco-2/TC7 cell line: a model to study trans-intestinal cholesterol excretion in atherogenic and diabetic dyslipidemia.

Camille DugardinOlivier BriandVéronique ToucheMarleen SchonewilleFrançois MoreauCédric Le MayAlbert K GroenOlivier BriandSophie Lestavel

Published in: Acta diabetologica (2016)

The human Caco-2/TC7 cell line appears a good in vitro model to investigate the enterocytic molecular mechanisms of TICE, which may help to identify intestinal molecular targets to enhance reverse cholesterol transport and fight against dyslipidemia.

Keyphrases

low density lipoprotein
endothelial cells
induced pluripotent stem cells
type diabetes
pluripotent stem cells
wound healing