The AUstralian multidomain Approach to Reduce dementia Risk by prOtecting brain health With lifestyle intervention study (AU-ARROW): A study protocol for a single-blind, multi-site, randomized controlled trial.
Samantha L GardenerStephanie J FullerSharon L NaismithLaura BakerMiia KivipeltoVictor L VillemagneStuart M GrievePaul YatesStephanie R Rainey-SmithJuliana ChenBelinda ThompsonNicola J ArmstrongMalika G FernandoCarolina Blagojevic CastroSilochna MeghwarRema RamanAndrew GleasonCatriona IrelandRoger ClarnetteKaarin J AnsteyKevin TaddeiManohar GargHamid R SohrabiRalph N MartinsPublished in: Alzheimer's & dementia (New York, N. Y.) (2024)
Study protocol for a single-blind, randomized controlled trial, the AU-ARROW Study.The AU-ARROW Study is a member of the World-Wide FINGERS (WW-FINGERS) initiative.AU-ARROW's primary outcome measure is change in a global composite cognitive score.Extra significance from amyloid PET imaging, brain MRI, and retinal biomarker tests.Leading to development of an innovative treatment plan to reduce cognitive decline.
Keyphrases
- randomized controlled trial
- cognitive decline
- pet imaging
- mild cognitive impairment
- study protocol
- public health
- healthcare
- magnetic resonance imaging
- mental health
- metabolic syndrome
- type diabetes
- physical activity
- clinical trial
- systematic review
- magnetic resonance
- diabetic retinopathy
- brain injury
- positron emission tomography
- subarachnoid hemorrhage
- blood brain barrier
- contrast enhanced
- double blind