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The Perioperative Use of Levosimendan as a Means of Optimizing the Surgical Outcome in Patients with Severe Heart Insufficiency Undergoing Cardiac Surgery.

Vasileios N LeivaditisKonstantinos GrapatsasPapaporfyriou AnastasiaMichail GalanisEfstratios KoletsisNikolaos CharokoposErich HaussmannVladislav KaplunovAthanasios PapatriantafyllouManfred Dahm
Published in: Journal of cardiovascular development and disease (2023)
This study provides evidence of several benefits associated with the perioperative use of levosimendan. However, further prospective randomized studies are warranted to standardize and comprehensively document the other perioperative therapies, in order to validate these findings and establish stronger conclusions.
Keyphrases
  • cardiac surgery
  • acute kidney injury
  • open label
  • patients undergoing
  • randomized controlled trial
  • phase iii
  • clinical trial
  • phase ii
  • study protocol